What are exosomes? By Dr Aminah May 2025

What are Autologous Exosomes?

Exosomes are tiny extracellular vesicles - microscopic messengers released by your body’s own cells. These vesicles carry growth signals and healing instructions between cells, especially in areas where repair or regeneration is needed.

At Novogenics, we extract these vesicles from your own blood (this is what “autologous” means) using a refined, sterile process. No donor material, no synthetic ingredients, and no foreign substances are used.

Why Platelet-Derived Exosomes Matter

Recent evidence shows that PRP-derived extracellular vesicles (EVs) - including exosomes - may contain greater concentrations of functional growth factors than PRP itself. These nanosized vesicles (typically 30–150 nm) are secreted naturally by activated platelets and serve as stable, bioavailable carriers of regenerative signals, including VEGF and other platelet-derived growth factors. Because exosomes are protected by a double lipid membrane, they are highly resistant to degradation and can penetrate cell membranes efficiently to deliver their molecular cargo. (include image here that is attached to email called novogenics infographic exosome)

At Novogenics, we use the Exomine™ system, a fully autologous platform that applies controlled shear forces via microlyser blades to activate platelets and release billions of exosomes directly from the patient’s own blood - all within the same sterile system. Flow cytometry markers (CD61+, CD41+, CD81+, CD9+) confirm that the exosomes are truly platelet-derived, while low CD45 and CD54 expression confirms minimal leukocyte contamination. Using this protocol, 4 mL of citrated plasma may yield over 100 billion vesicles, optimised in size (average ~104 nm) and purity. While the exact count can vary between patients, the T-Lab protocol ensures a consistently high-quality, reproducible product, setting a new gold standard for autologous regenerative therapy.

How Are They Different from PRP?

While PRP (Platelet-Rich Plasma) uses the whole plasma containing platelets, autologous exosome therapy goes a step further. It isolates the cell-free fraction - rich in nanosized extracellular vesicles - which can penetrate more deeply into tissue and stimulate more targeted repair.

This means:
- Less inflammation
- Faster recovery
- Longer-lasting signalling than PRP alone

For many women with thinning hair, especially where the follicles are still alive but dormant, exosome therapy can be a breakthrough.

Why Novogenics Uses Autologous Exosomes Only

Not all exosomes are created equal. Many commercial clinics offer exosome products derived from sources such as amniotic fluid, placenta, plants, or even salmon - often imported and not licensed for injection use in the UK. While early studies on these products suggest potential benefits, we cannot confidently predict the long-term effects of injecting material derived from other species or tissues into the human body.

At Novogenics, your safety is paramount. That’s why we use only autologous exosomes - regenerative messengers naturally derived from your own platelets. This method supports cellular repair and hair regrowth while eliminating the risks associated with foreign or synthetic biologics.
In short: your biology, your results - with nothing added and nothing to reject.

Using autologous exosomes, extracted from your own blood on the same day keeps our process:
- Legal and safe
- Biocompatible
- Ethical and hormone-free

You deserve a treatment that puts your health and your biology first.

Is It Right for Me?

Autologous EV-enriched plasma therapy may be right for you if:
- You’ve noticed early thinning around your parting or temples
- You’ve tried topical treatments without success
- You want a natural, drug-free approach to hair regrowth
- You value privacy, dignity, and medically-led care

Book Your Consultation

We see women from across Manchester, Cheshire, and the surrounding areas at our private clinic in Cheadle. Whether you're dealing with postpartum hair loss, PCOS, or just want a science-based approach, Novogenics is here to help.

Book your first consultation with Dr Aminah today.
Your body holds the answer. We help you unlock it.